STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yciYUncharacterized protein yciy; Belongs to the YciY family (57 aa)    
Predicted Functional Partners:
yedI
annotation not available
      
 0.827
yciX
annotation not available
      
 0.814
yigE
annotation not available
      
 0.790
ycjY
Putative hydrolase ycjy; Uncharacterized protein YcjY; Pseudogene fragment, MhpC family
      
 0.640
yhhZ
Putative hcp1 family polymorphic toxin protein; Belongs to the hcp1 family
  
     0.621
ybjO
annotation not available
      
 0.600
clsA
Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
       0.574
ariR
Probable rcsb/c two-component-system connector, global regulator of biofilm formation and acid-resistance; Probably a connector protein for RcsB/C regulation of biofilm and acid-resistance, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, via the Rcs phosphorelay. Regulates expression of genes involved in acid-resistance and biofilm formation, including the RcsB/C two- component system. May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition. Also confers resi [...]
  
     0.558
ymiA
annotation not available
      
 0.511
yjdP
Uncharacterized protein YjdP; Conserved hypothetical protein; conserved in EDL933 and CFT073; on opposite strand of the now deaccessioned phnQ (b4091)
  
     0.509
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.