STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Klhl12Kelch-like protein 12. (568 aa)    
Predicted Functional Partners:
Cul3
Cullin-3 isoform X1.
    
 0.954
Dvl1
Segment polarity protein dishevelled homolog DVL-1 isoform X1.
    
 0.894
Rbx1
E3 ubiquitin-protein ligase RBX1.
    
 0.711
Dvl2
Segment polarity protein dishevelled homolog DVL-2 isoform X1.
    
 0.664
Dvl3
Segment polarity protein dishevelled homolog DVL-3 isoform X1.
    
 0.658
Nanp
LOW QUALITY PROTEIN: N-acylneuraminate-9-phosphatase.
   
 
 0.625
Fbxl17
F-box and leucine-rich repeat protein 17.
    
 0.617
Cul1
Cullin 1.
    
 0.592
Pef1
Peflin.
    
 
 0.592
Rsph3
Radial spoke head protein 3 homolog.
   
   0.579
Your Current Organism:
Castor canadensis
NCBI taxonomy Id: 51338
Other names: American beaver, C. canadensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.