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erg-4 protein (Neurospora crassa) - STRING interaction network
"erg-4" - Sterol 24-C-methyltransferase in Neurospora crassa
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erg-4Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol (379 aa)    
Predicted Functional Partners:
erg-1
C-8 sterol isomerase (256 aa)
     
  0.984
EFNCRP00000000321
Putative uncharacterized protein (345 aa)
         
  0.904
erg-3
Delta(14)-sterol reductase (490 aa)
   
 
  0.881
EFNCRP00000004139
Delta(24(24(1)))-sterol reductase (584 aa)
     
 
  0.862
EFNCRP00000006022
Probable C-5 sterol desaturase (344 aa)
     
 
  0.852
EFNCRP00000005089
Cytochrome P450 61 (533 aa)
     
 
  0.847
EFNCRP00000002145
Cytochrome P450 51 (531 aa)
     
 
  0.847
EFNCRP00000001996
Putative uncharacterized protein (372 aa)
       
 
  0.839
EFNCRP00000004281
Related to lanosterol synthase (753 aa)
       
 
  0.839
EFNCRP00000006108
C-4 methylsterol oxidase, variant (306 aa)
     
 
  0.836
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 5141
Other names: Chrysonilia crassa, N. crassa, Neurospora, Neurospora crassa
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