STRINGSTRING
dre-2 protein (Neurospora crassa) - STRING interaction network
"dre-2" - Protein dre-2 in Neurospora crassa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dre-2Protein dre-2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein TAH18. Has anti-apoptotic effects in the cell. Involved in negative control of H(2)O(2)-induced cell death (333 aa)    
Predicted Functional Partners:
EFNCRP00000009485
Predicted protein (623 aa)
     
  0.958
EFNCRP00000009572
Putative uncharacterized protein (266 aa)
       
 
  0.909
B16M17.070
Monothiol glutaredoxin-5, mitochondrial (165 aa)
       
 
  0.908
nbp-35
Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (344 aa)
     
  0.715
EFNCRP00000009490
NADPH-cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 (692 aa)
       
  0.713
EFNCRP00000004953
Probable bifunctional P-450-NADPH-P450 reductase (1108 aa)
       
  0.713
cys-2
Putative uncharacterized protein (1030 aa)
       
  0.713
B9B15.100
Putative uncharacterized protein (622 aa)
       
  0.713
cfd-1
Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (304 aa)
     
  0.697
EFNCRP00000004592
Putative uncharacterized protein (309 aa)
     
  0.642
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 5141
Other names: Chrysonilia crassa, N. crassa, Neurospora, Neurospora crassa
Server load: low (8%) [HD]