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12F11.220 protein (Neurospora crassa) - STRING interaction network
"12F11.220" - Predicted protein in Neurospora crassa
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
12F11.220Predicted protein; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5’ splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5’ splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5’ splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment complex formation by stabilizing the base pairing of the 5’ end of the U1 snRNA and the 5’ splice-site region (216 aa)    
Predicted Functional Partners:
EFNCRP00000006139
Predicted protein (96 aa)
     
  0.988
EFNCRP00000007848
Predicted protein (415 aa)
     
  0.985
EFNCRP00000002157
Predicted protein (213 aa)
     
  0.981
EFNCRP00000000695
Small nuclear ribonucleoprotein Sm D1 (123 aa)
     
  0.976
B11N2.200
Probable small nuclear ribonucleoprotein SM D3 (116 aa)
     
  0.976
EFNCRP00000003517
Small nuclear ribonucleoprotein Sm D2 (119 aa)
     
  0.970
EFNCRP00000009652
Putative uncharacterized protein (85 aa)
     
  0.970
EFNCRP00000001835
Probable small nuclear ribonucleoprotein F (90 aa)
     
  0.959
EFNCRP00000006315
U2 small nuclear ribonucleoprotein A’ (252 aa)
     
  0.945
EFNCRP00000002976
Putative uncharacterized protein (901 aa)
     
  0.927
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 5141
Other names: Chrysonilia crassa, N. crassa, Neurospora, Neurospora crassa
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