STRINGSTRING
lys-5 protein (Neurospora crassa) - STRING interaction network
"lys-5" - Homocitrate synthase, mitochondrial in Neurospora crassa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lys-5Homocitrate synthase, mitochondrial (313 aa)    
Predicted Functional Partners:
29E8.300
Probable 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (779 aa)
 
  0.972
EFNCRP00000004781
Acetyl-CoA carboxylase (2275 aa)
   
  0.969
B11A5.190
Putative uncharacterized protein (809 aa)
   
  0.955
acu-5
Acetyl-coenzyme A synthetase (667 aa)
   
 
  0.931
EFNCRP00000009486
Acetyl-CoA acetyltransferase (430 aa)
   
 
  0.912
EFNCRP00000002222
Acetyl-CoA acetyltransferase (399 aa)
   
 
  0.912
ace-4
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (458 aa)
     
  0.911
acu-9
Malate synthase, glyoxysomal (542 aa)
         
  0.907
acu-8
Acetyl-CoA hydrolase (525 aa)
       
  0.902
leu-4
2-isopropylmalate synthase (625 aa)
         
    0.900
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 5141
Other names: Chrysonilia crassa, N. crassa, Neurospora, Neurospora crassa
Server load: low (12%) [HD]