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EFNCRP00000005971 protein (Neurospora crassa) - STRING interaction network
"EFNCRP00000005971" - Histone-lysine N-methyltransferase, H3 lysine-79 specific in Neurospora crassa
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
EFNCRP00000005971Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones (531 aa)    
Predicted Functional Partners:
set-1
Histone-lysine N-methyltransferase, H3 lysine-4 specific (1150 aa)
     
  0.915
set-2
Histone-lysine N-methyltransferase, H3 lysine-36 specific (954 aa)
     
  0.900
set-3
Predicted protein (1162 aa)
     
  0.841
dim-5
Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5 (331 aa)
       
  0.830
EFNCRP00000004675
Histone-lysine N-methyltransferase set-9 (783 aa)
     
 
  0.815
EFNCRP00000008798
Predicted protein (1115 aa)
     
 
  0.794
hH3
Histone H3 (136 aa)
       
  0.704
hH3v
Histone H3-like centromeric protein cse-4 (155 aa)
       
  0.678
hH4-1
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (103 aa)
     
  0.664
EFNCRP00000000141
Histone H4 (103 aa)
       
  0.646
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 5141
Other names: Chrysonilia crassa, N. crassa, Neurospora, Neurospora crassa
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