STRINGSTRING
nth-1 protein (Neurospora crassa) - STRING interaction network
"nth-1" - Putative uncharacterized protein in Neurospora crassa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nth-1Putative uncharacterized protein; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines (815 aa)    
Predicted Functional Partners:
EFNCRP00000001095
Putative uncharacterized protein (630 aa)
     
  0.847
B24N4.100
Putative uncharacterized protein (435 aa)
     
 
  0.760
erb-1
Ribosome biogenesis protein erb-1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome (779 aa)
           
  0.750
mus-38
Putative uncharacterized protein (957 aa)
     
 
  0.691
EFNCRP00000008331
Putative uncharacterized protein (484 aa)
     
 
  0.669
EFNCRP00000009813
Putative uncharacterized protein (490 aa)
   
 
  0.626
dcl-1
Dicer-like protein 1 (1584 aa)
   
 
  0.610
preg
Nuc-1 negative regulatory protein preg (475 aa)
     
   
  0.605
pyr-3
Protein pyrABCN (1832 aa)
         
  0.593
EFNCRP00000006105
DNA topoisomerase 2 (1909 aa)
   
 
  0.587
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 5141
Other names: Chrysonilia crassa, N. crassa, Neurospora, Neurospora crassa
Server load: low (11%) [HD]