STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1-1Nuclear distribution protein PAC1-1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (460 aa)    
Predicted Functional Partners:
SMAC_00761
Putative dynein heavy chain protein.
    
 0.953
SMAC_00918
Lysophospholipase.
     
  0.911
SMAC_05168
WGS project CABT00000000 data, contig 2.8.
     
 0.908
SMAC_07063
Putative phospholipase.
     
 0.908
PAC1-2
Nuclear distribution protein PAC1-2; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.
  
  
 
0.901
SMAC_05367
WGS project CABT00000000 data, contig 2.25; Belongs to the membrane-bound acyltransferase family.
     
  0.900
SMAC_05668
Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.
     
  0.900
SMAC_08826
WGS project CABT00000000 data, contig 2.66.
    
 
 0.830
SMAC_04637
WGS project CABT00000000 data, contig 2.20.
   
 0.827
SMAC_01640
WGS project CABT00000000 data, contig 2.4.
    
 0.803
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.