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LIS1-1 protein (Sordaria macrospora) - STRING interaction network
"LIS1-1" - Nuclear distribution protein PAC1-1 in Sordaria macrospora
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LIS1-1Nuclear distribution protein PAC1-1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein- mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family (460 aa)    
Predicted Functional Partners:
SMAC_00761
Dynein heavy chain protein (4360 aa)
       
 
  0.905
SMAC_00918
Lysophospholipase (845 aa)
         
    0.900
SMAC_05668
Patatin-like phospholipase domain-containing protein; Lipid hydrolase (793 aa)
         
    0.900
SMAC_07211
WGS project CABT00000000 data, contig 2.42 (1366 aa)
       
 
  0.843
SMAC_05168
WGS project CABT00000000 data, contig 2.8 (748 aa)
       
  0.843
SMAC_07063
Putative phospholipase (587 aa)
       
  0.819
LIS1-2
Nuclear distribution protein PAC1-2; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein- mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family (486 aa)
   
   
 
0.802
SMAC_05367
WGS project CABT00000000 data, contig 2.25; Belongs to the membrane-bound acyltransferase family (592 aa)
         
    0.800
SMAC_00349
WGS project CABT00000000 data, contig 2.1 (696 aa)
       
 
  0.759
SMAC_08826
WGS project CABT00000000 data, contig 2.66 (701 aa)
       
 
  0.741
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 5147
Other names: S. macrospora, Sordaria macrospora
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