STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purMPhosphoribosylformylglycinamidine cyclo-ligase; Psort-B: Unknown cell location; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; HMMPfam:IPR000728; HMMPfam:IPR010918; HMMTigr:IPR004733; K01933 phosphoribosylformylglycinamidine cyclo-ligase. (341 aa)    
Predicted Functional Partners:
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 0.999
purD
Phosphoribosylamine--glycine ligase; Psort-B: Cytoplasmic, score:8.87; COG0151 Phosphoribosylamine-glycine ligase; HMMPfam:IPR000115; Gene3D:IPR000115; Gene3D:IPR013815; Gene3D:IPR013816; Gene3D:IPR013817; HMMTigr:IPR000115; ScanRegExp:IPR000115; superfamily:IPR011054; K01945 phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
 0.999
ACR71580.1
Psort-B: Cytoplasmic, score:8.87; COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; HMMPfam:IPR010918; HMMTigr:IPR010141; K01952 phosphoribosylformylglycinamidine synthase.
 
 
 0.999
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 0.996
purE
Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
  
 0.995
purC
Psort-B: Cytoplasmic, score:8.87; COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HMMPfam:IPR001636; BlastProDom:IPR001636; Gene3D:IPR013816; HMMPanther:IPR001636; HMMTigr:IPR001636; ScanRegExp:IPR001636; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase.
  
  
 0.952
ACR71477.1
Adenylosuccinate lyase; Psort-B: Cytoplasmic, score:8.87; COG0015 Adenylosuccinate lyase; HMMPfam:IPR000362; HMMTigr:IPR004769; ScanRegExp:IPR000362; superfamily:IPR008948; K01756 adenylosuccinate lyase.
  
 
 0.942
guaB
Malate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
  
 0.927
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
     
 0.802
ACR72953.1
Hypothetical protein; Psort-B: CytoplasmicMembrane, score:9.99.
   
    0.764
Your Current Organism:
Eubacterium eligens
NCBI taxonomy Id: 515620
Other names: Eubacterium eligens ATCC 27750, [. eligens ATCC 27750, [Eubacterium] eligens ATCC 27750
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