STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACR72860.1Protein phosphatase; Psort-B: Cytoplasmic, score:8.87; COG2208 Serine phosphatase RsbU, regulator of sigma subunit; HMMPfam:IPR010822; HMMSmart:IPR001932; K01090 protein phosphatase. (370 aa)    
Predicted Functional Partners:
ACR71742.1
Psort-B: CytoplasmicMembrane, score:9.99; NOG09744 non supervised orthologous group; HMMPfam:IPR005081; K06383 stage II sporulation protein GA (sporulation sigma-E factor processing peptidase).
  
  
 0.921
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.903
ACR72865.1
AbrB family transcriptional regulator, stage V sporulation protein T; Psort-B: Cytoplasmic, score:9.98; COG2002 Regulators of stationary/sporulation gene expression; HMMPfam:IPR007159; HMMTigr:IPR006339; K04769 AbrB family transcriptional regulator, stage V sporulation protein T.
 
   
 0.895
ACR72863.1
Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; NOG13819 non supervised orthologous group; HMMPfam:IPR012504; HMMTigr:IPR012504.
 
     0.894
ACR71197.1
Stage II sporulation protein R; Psort-B: Unknown cell location; NOG13215 non supervised orthologous group; HMMTigr:IPR014202; K06387 stage II sporulation protein R.
  
   
 0.885
ACR71209.1
Putative DeoR family transcriptional regulator, stage III sporulation protein D; Psort-B: Cytoplasmic, score:8.87; NOG13855 non supervised orthologous group; HMMTigr:IPR014208; ScanRegExp:IPR001034; K06283 putative DeoR family transcriptional regulator, stage III sporulation protein D.
  
   
 0.879
ACR72077.1
Two-component system, sporulation family, response regulator, stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.879
ACR72600.1
Stage II sporulation protein AA (anti-sigma F factor antagonist); Psort-B: Cytoplasmic, score:8.87; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); HMMPfam:IPR002645; BlastProDom:IPR003658; Gene3D:IPR002645; HMMTigr:IPR003658; superfamily:IPR002645; K06378 stage II sporulation protein AA (anti-sigma F factor antagonist); Belongs to the anti-sigma-factor antagonist family.
  
  
 0.872
ACR72326.1
Psort-B: Cytoplasmic, score:9.98; COG1191 DNA-directed RNA polymerase specialized sigma subunit; HMMPfam:IPR007624; HMMPfam:IPR007627; HMMPfam:IPR007630; Gene3D:IPR011991; HMMTigr:IPR014284; HMMTigr:IPR014322; ScanRegExp:IPR000943; superfamily:IPR013324; superfamily:IPR013325; K03091 RNA polymerase sporulation-specific sigma factor; Belongs to the sigma-70 factor family.
  
  
 0.870
ACR72205.1
Stage II sporulation protein P; Psort-B: Cytoplasmic, score:8.87; NOG13213 non supervised orthologous group; HMMPfam:IPR010897; K06385 stage II sporulation protein P.
  
   
 0.867
Your Current Organism:
Eubacterium eligens
NCBI taxonomy Id: 515620
Other names: Eubacterium eligens ATCC 27750, [. eligens ATCC 27750, [Eubacterium] eligens ATCC 27750
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.