node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dtur_1324 | Dtur_1471 | Dtur_1324 | Dtur_1471 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: dth:DICTH_1361 pyrimidine-nucleoside phosphorylase. | 0.993 |
Dtur_1324 | Dtur_1794 | Dtur_1324 | Dtur_1794 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | 0.912 |
Dtur_1324 | surE | Dtur_1324 | Dtur_1108 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.907 |
Dtur_1324 | tdk | Dtur_1324 | Dtur_0803 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | PFAM: thymidine kinase; KEGG: dth:DICTH_0645 thymidine kinase. | 0.920 |
Dtur_1471 | Dtur_1324 | Dtur_1471 | Dtur_1324 | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: dth:DICTH_1361 pyrimidine-nucleoside phosphorylase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.993 |
Dtur_1471 | Dtur_1794 | Dtur_1471 | Dtur_1794 | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: dth:DICTH_1361 pyrimidine-nucleoside phosphorylase. | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | 0.910 |
Dtur_1471 | surE | Dtur_1471 | Dtur_1108 | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: dth:DICTH_1361 pyrimidine-nucleoside phosphorylase. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.922 |
Dtur_1471 | tdk | Dtur_1471 | Dtur_0803 | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: dth:DICTH_1361 pyrimidine-nucleoside phosphorylase. | PFAM: thymidine kinase; KEGG: dth:DICTH_0645 thymidine kinase. | 0.926 |
Dtur_1471 | upp | Dtur_1471 | Dtur_0811 | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: dth:DICTH_1361 pyrimidine-nucleoside phosphorylase. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.946 |
Dtur_1794 | Dtur_1324 | Dtur_1794 | Dtur_1324 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.912 |
Dtur_1794 | Dtur_1471 | Dtur_1794 | Dtur_1471 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: dth:DICTH_1361 pyrimidine-nucleoside phosphorylase. | 0.910 |
Dtur_1794 | dut | Dtur_1794 | Dtur_0831 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
Dtur_1794 | surE | Dtur_1794 | Dtur_1108 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
Dtur_1794 | tdk | Dtur_1794 | Dtur_0803 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | PFAM: thymidine kinase; KEGG: dth:DICTH_0645 thymidine kinase. | 0.919 |
Dtur_1794 | thyX | Dtur_1794 | Dtur_0802 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.900 |
Dtur_1794 | tmk | Dtur_1794 | Dtur_0787 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.911 |
Dtur_1794 | upp | Dtur_1794 | Dtur_0811 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.903 |
dut | Dtur_1794 | Dtur_0831 | Dtur_1794 | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. | 0.900 |
dut | glyA | Dtur_0831 | Dtur_0810 | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.496 |
dut | prfA | Dtur_0831 | Dtur_0805 | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.476 |