node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dtur_0804 | Dtur_0807 | Dtur_0804 | Dtur_0807 | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.794 |
Dtur_0804 | Dtur_0809 | Dtur_0804 | Dtur_0809 | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | KEGG: dth:DICTH_0651 ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | 0.815 |
Dtur_0804 | glyA | Dtur_0804 | Dtur_0810 | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.794 |
Dtur_0804 | murA | Dtur_0804 | Dtur_0812 | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.794 |
Dtur_0804 | prfA | Dtur_0804 | Dtur_0805 | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.804 |
Dtur_0804 | prmC | Dtur_0804 | Dtur_0806 | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.978 |
Dtur_0804 | rpmE | Dtur_0804 | Dtur_0801 | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | Ribosomal protein L31; Binds the 23S rRNA. | 0.794 |
Dtur_0804 | tdk | Dtur_0804 | Dtur_0803 | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | PFAM: thymidine kinase; KEGG: dth:DICTH_0645 thymidine kinase. | 0.805 |
Dtur_0804 | thyX | Dtur_0804 | Dtur_0802 | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.801 |
Dtur_0807 | Dtur_0804 | Dtur_0807 | Dtur_0804 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | 0.794 |
Dtur_0807 | Dtur_0809 | Dtur_0807 | Dtur_0809 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | KEGG: dth:DICTH_0651 ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | 0.815 |
Dtur_0807 | glyA | Dtur_0807 | Dtur_0810 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.950 |
Dtur_0807 | murA | Dtur_0807 | Dtur_0812 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.794 |
Dtur_0807 | prfA | Dtur_0807 | Dtur_0805 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.802 |
Dtur_0807 | prmC | Dtur_0807 | Dtur_0806 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.916 |
Dtur_0807 | rpmE | Dtur_0807 | Dtur_0801 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Ribosomal protein L31; Binds the 23S rRNA. | 0.802 |
Dtur_0807 | tdk | Dtur_0807 | Dtur_0803 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | PFAM: thymidine kinase; KEGG: dth:DICTH_0645 thymidine kinase. | 0.797 |
Dtur_0807 | thyX | Dtur_0807 | Dtur_0802 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.778 |
Dtur_0809 | Dtur_0804 | Dtur_0809 | Dtur_0804 | KEGG: dth:DICTH_0651 ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | PFAM: protein of unknown function DUF1385; KEGG: dth:DICTH_0646 conserved membrane protein YqhQ. | 0.815 |
Dtur_0809 | Dtur_0807 | Dtur_0809 | Dtur_0807 | KEGG: dth:DICTH_0651 ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.815 |