node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dtur_1253 | ftsA | Dtur_1253 | Dtur_1243 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.944 |
Dtur_1253 | ftsZ | Dtur_1253 | Dtur_1242 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.852 |
Dtur_1253 | mraZ | Dtur_1253 | Dtur_1256 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: dth:DICTH_1141 MraZ protein; Belongs to the MraZ family. | 0.888 |
Dtur_1253 | murB | Dtur_1253 | Dtur_1245 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.944 |
Dtur_1253 | murC | Dtur_1253 | Dtur_1246 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.966 |
Dtur_1253 | murD | Dtur_1253 | Dtur_1249 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.972 |
Dtur_1253 | murE | Dtur_1253 | Dtur_1252 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.973 |
Dtur_1253 | murF | Dtur_1253 | Dtur_1251 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.972 |
Dtur_1253 | murG | Dtur_1253 | Dtur_1247 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.959 |
Dtur_1253 | rsmH | Dtur_1253 | Dtur_1255 | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.911 |
ftsA | Dtur_1253 | Dtur_1243 | Dtur_1253 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Peptidoglycan glycosyl transferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: dth:DICTH_1138 penicillin-binding protein 2B, putative. | 0.944 |
ftsA | ftsZ | Dtur_1243 | Dtur_1242 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.999 |
ftsA | mraZ | Dtur_1243 | Dtur_1256 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: dth:DICTH_1141 MraZ protein; Belongs to the MraZ family. | 0.843 |
ftsA | murB | Dtur_1243 | Dtur_1245 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.843 |
ftsA | murC | Dtur_1243 | Dtur_1246 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.912 |
ftsA | murD | Dtur_1243 | Dtur_1249 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.935 |
ftsA | murE | Dtur_1243 | Dtur_1252 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.880 |
ftsA | murF | Dtur_1243 | Dtur_1251 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.890 |
ftsA | murG | Dtur_1243 | Dtur_1247 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.907 |
ftsA | rsmH | Dtur_1243 | Dtur_1255 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.868 |