node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dtur_1423 | purC | Dtur_1423 | Dtur_0270 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.995 |
Dtur_1423 | purD | Dtur_1423 | Dtur_1416 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: dth:DICTH_1310 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Belongs to the GARS family. | 0.974 |
Dtur_1423 | purE | Dtur_1423 | Dtur_0269 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.928 |
Dtur_1423 | purF | Dtur_1423 | Dtur_1419 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.986 |
Dtur_1423 | purH | Dtur_1423 | Dtur_0847 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: dth:DICTH_0690 bifunctional purine biosynthesis protein PurH; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.992 |
Dtur_1423 | purL | Dtur_1423 | Dtur_1420 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.964 |
Dtur_1423 | purM | Dtur_1423 | Dtur_1418 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: dth:DICTH_1312 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.962 |
Dtur_1423 | purN | Dtur_1423 | Dtur_1417 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.956 |
Dtur_1423 | purQ | Dtur_1423 | Dtur_1421 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.961 |
Dtur_1423 | purS | Dtur_1423 | Dtur_1422 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.952 |
purC | Dtur_1423 | Dtur_0270 | Dtur_1423 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: dth:DICTH_1317 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.995 |
purC | purD | Dtur_0270 | Dtur_1416 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | KEGG: dth:DICTH_1310 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Belongs to the GARS family. | 0.958 |
purC | purE | Dtur_0270 | Dtur_0269 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purC | purF | Dtur_0270 | Dtur_1419 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.946 |
purC | purH | Dtur_0270 | Dtur_0847 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | KEGG: dth:DICTH_0690 bifunctional purine biosynthesis protein PurH; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.963 |
purC | purL | Dtur_0270 | Dtur_1420 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.946 |
purC | purM | Dtur_0270 | Dtur_1418 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | KEGG: dth:DICTH_1312 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.941 |
purC | purN | Dtur_0270 | Dtur_1417 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.958 |
purC | purQ | Dtur_0270 | Dtur_1421 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.941 |
purC | purS | Dtur_0270 | Dtur_1422 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: dth:DICTH_0002 phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.935 |