node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cpar_0251 | guaA | Cpar_0251 | Cpar_1868 | PFAM: Class I peptide chain release factor; KEGG: cte:CT1983 hypothetical protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.420 |
Cpar_0251 | mfd | Cpar_0251 | Cpar_0654 | PFAM: Class I peptide chain release factor; KEGG: cte:CT1983 hypothetical protein. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.713 |
Cpar_0251 | prfA | Cpar_0251 | Cpar_0069 | PFAM: Class I peptide chain release factor; KEGG: cte:CT1983 hypothetical protein. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.845 |
Cpar_0251 | pth | Cpar_0251 | Cpar_1258 | PFAM: Class I peptide chain release factor; KEGG: cte:CT1983 hypothetical protein. | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.581 |
Cpar_0251 | rplA | Cpar_0251 | Cpar_1886 | PFAM: Class I peptide chain release factor; KEGG: cte:CT1983 hypothetical protein. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.921 |
Cpar_0251 | rplY | Cpar_0251 | Cpar_0795 | PFAM: Class I peptide chain release factor; KEGG: cte:CT1983 hypothetical protein. | Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.827 |
guaA | Cpar_0251 | Cpar_1868 | Cpar_0251 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | PFAM: Class I peptide chain release factor; KEGG: cte:CT1983 hypothetical protein. | 0.420 |
guaA | polA | Cpar_1868 | Cpar_0523 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.750 |
guaA | pth | Cpar_1868 | Cpar_1258 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.535 |
guaA | rplA | Cpar_1868 | Cpar_1886 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.952 |
guaA | rplY | Cpar_1868 | Cpar_0795 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.413 |
guaA | tilS | Cpar_1868 | Cpar_0572 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.468 |
guaA | ychF | Cpar_1868 | Cpar_1749 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.686 |
hppA | pth | Cpar_1257 | Cpar_1258 | V-type H(+)-translocating pyrophosphatase; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily. | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.585 |
mfd | Cpar_0251 | Cpar_0654 | Cpar_0251 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | PFAM: Class I peptide chain release factor; KEGG: cte:CT1983 hypothetical protein. | 0.713 |
mfd | polA | Cpar_0654 | Cpar_0523 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.624 |
mfd | pth | Cpar_0654 | Cpar_1258 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.664 |
mfd | tilS | Cpar_0654 | Cpar_0572 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.572 |
polA | guaA | Cpar_0523 | Cpar_1868 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.750 |
polA | mfd | Cpar_0523 | Cpar_0654 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.624 |