node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cpar_1416 | Cpar_1417 | Cpar_1416 | Cpar_1417 | KEGG: cyt:cce_2701 hypothetical protein. | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | 0.982 |
Cpar_1416 | Cpar_1848 | Cpar_1416 | Cpar_1848 | KEGG: cyt:cce_2701 hypothetical protein. | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cte:CT0191 ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.608 |
Cpar_1416 | Cpar_1971 | Cpar_1416 | Cpar_1971 | KEGG: cyt:cce_2701 hypothetical protein. | PFAM: AAA ATPase central domain protein; Clp domain protein; SMART: AAA ATPase; KEGG: cte:CT2281 ATP-dependent Clp protease, ATP-binding subunit ClpB; Belongs to the ClpA/ClpB family. | 0.608 |
Cpar_1416 | clpP | Cpar_1416 | Cpar_0405 | KEGG: cyt:cce_2701 hypothetical protein. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.611 |
Cpar_1416 | dnaJ | Cpar_1416 | Cpar_1573 | KEGG: cyt:cce_2701 hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.835 |
Cpar_1416 | dnaK | Cpar_1416 | Cpar_0645 | KEGG: cyt:cce_2701 hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.933 |
Cpar_1416 | groL | Cpar_1416 | Cpar_1366 | KEGG: cyt:cce_2701 hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.841 |
Cpar_1416 | hrcA | Cpar_1416 | Cpar_1575 | KEGG: cyt:cce_2701 hypothetical protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.779 |
Cpar_1417 | Cpar_1416 | Cpar_1417 | Cpar_1416 | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | KEGG: cyt:cce_2701 hypothetical protein. | 0.982 |
Cpar_1417 | Cpar_1848 | Cpar_1417 | Cpar_1848 | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cte:CT0191 ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | 0.800 |
Cpar_1417 | Cpar_1971 | Cpar_1417 | Cpar_1971 | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | PFAM: AAA ATPase central domain protein; Clp domain protein; SMART: AAA ATPase; KEGG: cte:CT2281 ATP-dependent Clp protease, ATP-binding subunit ClpB; Belongs to the ClpA/ClpB family. | 0.800 |
Cpar_1417 | clpP | Cpar_1417 | Cpar_0405 | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.636 |
Cpar_1417 | dnaJ | Cpar_1417 | Cpar_1573 | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.995 |
Cpar_1417 | groL | Cpar_1417 | Cpar_1366 | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.872 |
Cpar_1417 | grpE | Cpar_1417 | Cpar_1574 | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.946 |
Cpar_1417 | hrcA | Cpar_1417 | Cpar_1575 | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.779 |
Cpar_1417 | rplJ | Cpar_1417 | Cpar_1885 | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.545 |
Cpar_1848 | Cpar_1416 | Cpar_1848 | Cpar_1416 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cte:CT0191 ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | KEGG: cyt:cce_2701 hypothetical protein. | 0.608 |
Cpar_1848 | Cpar_1417 | Cpar_1848 | Cpar_1417 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cte:CT0191 ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family. | 0.800 |
Cpar_1848 | clpP | Cpar_1848 | Cpar_0405 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cte:CT0191 ATP-dependent Clp protease, ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.914 |