node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cpar_0264 | Cpar_2014 | Cpar_0264 | Cpar_2014 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cte:CT1951 8-amino-7-oxononanoate synthase. | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | 0.909 |
Cpar_0264 | Cpar_2015 | Cpar_0264 | Cpar_2015 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cte:CT1951 8-amino-7-oxononanoate synthase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.922 |
Cpar_0264 | bioA | Cpar_0264 | Cpar_2011 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cte:CT1951 8-amino-7-oxononanoate synthase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.966 |
Cpar_0264 | bioB | Cpar_0264 | Cpar_2016 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cte:CT1951 8-amino-7-oxononanoate synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.779 |
Cpar_0264 | bioD | Cpar_0264 | Cpar_2012 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cte:CT1951 8-amino-7-oxononanoate synthase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.831 |
Cpar_0264 | birA | Cpar_0264 | Cpar_2017 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cte:CT1951 8-amino-7-oxononanoate synthase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.486 |
Cpar_2014 | Cpar_0264 | Cpar_2014 | Cpar_0264 | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cte:CT1951 8-amino-7-oxononanoate synthase. | 0.909 |
Cpar_2014 | Cpar_2015 | Cpar_2014 | Cpar_2015 | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.985 |
Cpar_2014 | Cpar_2018 | Cpar_2014 | Cpar_2018 | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: cte:CT0054 N-acetylmuramoyl-L-alanine amidase. | 0.421 |
Cpar_2014 | bioA | Cpar_2014 | Cpar_2011 | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.809 |
Cpar_2014 | bioB | Cpar_2014 | Cpar_2016 | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.899 |
Cpar_2014 | bioC | Cpar_2014 | Cpar_2013 | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.978 |
Cpar_2014 | bioD | Cpar_2014 | Cpar_2012 | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.951 |
Cpar_2014 | birA | Cpar_2014 | Cpar_2017 | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.785 |
Cpar_2015 | Cpar_0264 | Cpar_2015 | Cpar_0264 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cte:CT1951 8-amino-7-oxononanoate synthase. | 0.922 |
Cpar_2015 | Cpar_2014 | Cpar_2015 | Cpar_2014 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: protein of unknown function DUF452; KEGG: cte:CT0050 hypothetical protein. | 0.985 |
Cpar_2015 | Cpar_2018 | Cpar_2015 | Cpar_2018 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; KEGG: cte:CT0054 N-acetylmuramoyl-L-alanine amidase. | 0.421 |
Cpar_2015 | bioA | Cpar_2015 | Cpar_2011 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.989 |
Cpar_2015 | bioB | Cpar_2015 | Cpar_2016 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.970 |
Cpar_2015 | bioC | Cpar_2015 | Cpar_2013 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.905 |