STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ctha_2180TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: chu:CHU_1086 dihydrolipoyl dehydrogenase (dihydrolipoamide dehydrogenase). (477 aa)    
Predicted Functional Partners:
Ctha_0429
PFAM: dehydrogenase E1 component; Transketolase central region; Transketolase domain protein; KEGG: sru:SRU_0576 2-oxoisovalerate dehydrogenase, E1 component, alpha and beta subunit.
 
 0.999
Ctha_2202
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: sru:SRU_0811 2-oxo acid dehydrogenases acyltransferase (catalytic domain) protein.
 0.999
Ctha_2297
PFAM: dehydrogenase E1 component; Transketolase central region; Transketolase domain protein; KEGG: bfr:BF1622 2-oxoisovalerate dehydrogenase beta subunit.
 
 0.999
Ctha_2569
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase central region; KEGG: sus:Acid_5307 alpha-ketoglutarate decarboxylase.
 
 0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.984
Ctha_0129
PFAM: glycine cleavage H-protein; KEGG: aby:ABAYE2103 glycine cleavage complex protein H, carrier of aminomethyl moiety via covalently bound lipoyl cofactor.
 
  
 0.977
Ctha_0140
PFAM: glycine cleavage H-protein; KEGG: aae:aq_944 glycine cleavage system protein H.
 
  
 0.977
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.975
Ctha_0743
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cte:CT1628 pyruvate flavodoxin/ferrodoxin oxidoreductase.
    
 0.940
gcvPB
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
 
 
 0.935
Your Current Organism:
Chloroherpeton thalassium
NCBI taxonomy Id: 517418
Other names: C. thalassium ATCC 35110, Chloroherpeton thalassium ATCC 35110, Chloroherpeton thalassium str. ATCC 35110, Chloroherpeton thalassium strain ATCC 35110
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