STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ctha_2197KEGG: sru:SRU_2119 A/G-specific adenine glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: NUDIX hydrolase; HhH-GPD family protein; SMART: iron-sulfur cluster loop. (360 aa)    
Predicted Functional Partners:
Ctha_1293
KEGG: cph:Cpha266_2513 exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
    
 0.800
Ctha_2196
PFAM: 8-oxoguanine DNA glycosylase domain protein; SMART: HhH-GPD family protein; KEGG: cte:CT0996 8-oxoguanine DNA glycosylase, putative.
  
  
 0.778
Ctha_1687
KEGG: cyt:cce_2443 hypothetical protein.
    
 0.774
Ctha_1688
KEGG: cyt:cce_2442 hypothetical protein.
    
 0.774
Ctha_2198
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tma:TM1177 hypothetical protein.
     
 0.498
Ctha_2199
PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; KEGG: cph:Cpha266_0208 NAD-dependent epimerase/dehydratase.
       0.482
Ctha_0842
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.448
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.429
Your Current Organism:
Chloroherpeton thalassium
NCBI taxonomy Id: 517418
Other names: C. thalassium ATCC 35110, Chloroherpeton thalassium ATCC 35110, Chloroherpeton thalassium str. ATCC 35110, Chloroherpeton thalassium strain ATCC 35110
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