STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT37944.1Uncharacterized protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (250 aa)    
Predicted Functional Partners:
AKT36167.1
Uncharacterized protein.
   
 
 0.783
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.760
AKT40867.1
Uncharacterized protein.
 
  
 0.753
AKT44022.1
Nif3-like dinuclear metal center hexameric protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
 
  
 0.742
smpB
Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.697
AKT39230.1
Uncharacterized protein.
   
 
 0.697
gpmA
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.565
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.538
AKT37946.1
Uncharacterized protein.
  
    0.518
AKT37943.1
Uncharacterized protein.
       0.516
Your Current Organism:
Chondromyces crocatus
NCBI taxonomy Id: 52
Other names: C. crocatus, DSM 14714, JCM 12616, Myxobotrys variabilis, TC 601, strain Cm c5
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