STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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mtdMethylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (280 aa)    
Predicted Functional Partners:
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
  
 
 0.982
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
 
  
 0.964
Mpal_0087
TIGRFAM: coenzyme F420 hydrogenase, subunit beta; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: mhu:Mhun_2329 coenzyme F420-reducing hydrogenase subunit beta.
  
 
 0.960
Mpal_2707
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: mem:Memar_0331 coenzyme F420 hydrogenase/dehydrogenase beta subunit.
  
 
 0.948
Mpal_0084
TIGRFAM: coenzyme F420 hydrogenase, subunit alpha; PFAM: nickel-dependent hydrogenase large subunit; KEGG: mem:Memar_2174 nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
  
 0.946
Mpal_0086
KEGG: mla:Mlab_0013 coenzyme F420-reducing hydrogenase, gamma subunit; TIGRFAM: coenzyme F420 hydrogenase, subunit gamma; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; NADH ubiquinone oxidoreductase 20 kDa subunit.
  
  
  0.938
fae-hps
Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
  
  
 0.938
Mpal_0085
TIGRFAM: hydrogenase maturation protease; coenzyme F420-reducing hydrogenase delta subunit; PFAM: peptidase M52 hydrogen uptake protein; KEGG: mem:Memar_2175 hydrogenase maturation protease.
  
  
 0.928
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.900
mtrE
Tetrahydromethanopterin S-methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
   
 0.828
Your Current Organism:
Methanosphaerula palustris
NCBI taxonomy Id: 521011
Other names: Candidatus Methanosphaerula palustris E1-9c, M. palustris E1-9c, Methanosphaerula palustris E1-9c, Methanosphaerula palustris str. E1-9c, Methanosphaerula palustris strain E1-9c
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