STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mpal_0439TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mbn:Mboo_2164 D-3-phosphoglycerate dehydrogenase. (532 aa)    
Predicted Functional Partners:
Mpal_0975
PFAM: phosphoribulokinase/uridine kinase; KEGG: mem:Memar_1934 phosphoribulokinase/uridine kinase.
   
 0.960
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.930
Mpal_2019
KEGG: mem:Memar_0702 proposed homoserine kinase; TIGRFAM: phosphonopyruvate decarboxylase-related protein; proposed homoserine kinase; PFAM: metalloenzyme domain protein; Homoserine kinase family protein.
 
  
 0.921
apgM
Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.910
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.798
rpl6
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.795
Mpal_0418
Alanine--glyoxylate transaminase; PFAM: aminotransferase class V; aminotransferase class-III; KEGG: mbn:Mboo_0053 aminotransferase, class V.
 
  
 0.785
rpl10e
TIGRFAM: ribosomal protein L10.e; PFAM: ribosomal protein L16; KEGG: mem:Memar_0848 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family.
  
 
 0.777
rpl22
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
   
 
 0.765
Mpal_1993
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: mem:Memar_0971 homoserine dehydrogenase.
 
 
 0.762
Your Current Organism:
Methanosphaerula palustris
NCBI taxonomy Id: 521011
Other names: Candidatus Methanosphaerula palustris E1-9c, M. palustris E1-9c, Methanosphaerula palustris E1-9c, Methanosphaerula palustris str. E1-9c, Methanosphaerula palustris strain E1-9c
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