STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmkTIGRFAM: cytidylate kinase; KEGG: mem:Memar_0590 cytidylate kinase. (176 aa)    
Predicted Functional Partners:
rpl24
Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
 
    0.956
Mpal_0459
PFAM: Ribosomal protein L32e; KEGG: mhu:Mhun_2236 50S ribosomal protein L32e.
 
    0.952
rpl22
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
 
    0.948
rpl5
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
    0.946
rps4e
PFAM: RNA-binding S4 domain protein; KOW domain protein; Ribosomal protein S4E domain protein; Ribosomal protein S4E, central domain protein; KEGG: mbn:Mboo_0544 30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.
  
    0.942
rpl15
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
    0.942
rpl14
Rhodopsin family protein GPCR superfamily; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
    0.940
rpl4
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
  
    0.939
rps8
Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
  
    0.938
rpl6
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
    0.937
Your Current Organism:
Methanosphaerula palustris
NCBI taxonomy Id: 521011
Other names: Candidatus Methanosphaerula palustris E1-9c, M. palustris E1-9c, Methanosphaerula palustris E1-9c, Methanosphaerula palustris str. E1-9c, Methanosphaerula palustris strain E1-9c
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