STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmBProteasome, beta-type subunit, conserved site; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (211 aa)    
Predicted Functional Partners:
psmA
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.999
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
 
 0.939
Mpal_0507
26S proteasome subunit P45 family; KEGG: mbn:Mboo_1458 proteasome-activating nucleotidase; TIGRFAM: 26S proteasome subunit P45 family; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family.
  
 0.929
Mpal_0777
PFAM: beta-lactamase domain protein; KH type 1 domain protein; RNA-metabolising metallo-beta-lactamase; SMART: KH domain protein; KEGG: mbn:Mboo_1385 beta-lactamase domain-containing protein.
 
   
 0.908
Mpal_0311
KEGG: mbn:Mboo_0210 hypothetical protein.
   
 0.870
Mpal_1140
SMART: Mov34/MPN/PAD-1 family protein; KEGG: wsu:WS1005 hypothetical protein.
   
 0.870
rpl40e
KEGG: mbn:Mboo_0238 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.842
Mpal_0776
PFAM: major facilitator superfamily MFS_1; KEGG: mem:Memar_1200 major facilitator transporter.
 
     0.794
Mpal_0262
KEGG: mem:Memar_2157 AAA family ATPase, CDC48 subfamily protein; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
 
 0.734
Mpal_0801
KEGG: mem:Memar_1561 AAA family ATPase, CDC48 subfamily protein; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; SMART: AAA ATPase.
 
 0.733
Your Current Organism:
Methanosphaerula palustris
NCBI taxonomy Id: 521011
Other names: Candidatus Methanosphaerula palustris E1-9c, M. palustris E1-9c, Methanosphaerula palustris E1-9c, Methanosphaerula palustris str. E1-9c, Methanosphaerula palustris strain E1-9c
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