node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpal_2121 | Mpal_2411 | Mpal_2121 | Mpal_2411 | PFAM: Orotidine 5'-phosphate decarboxylase; Dimethylmenaquinone methyltransferase; KEGG: mem:Memar_0744 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator. | TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS); KEGG: mem:Memar_1507 sugar isomerase (SIS). | 0.996 |
Mpal_2121 | fae-hps | Mpal_2121 | Mpal_1036 | PFAM: Orotidine 5'-phosphate decarboxylase; Dimethylmenaquinone methyltransferase; KEGG: mem:Memar_0744 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator. | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | 0.934 |
Mpal_2121 | rpiA | Mpal_2121 | Mpal_0583 | PFAM: Orotidine 5'-phosphate decarboxylase; Dimethylmenaquinone methyltransferase; KEGG: mem:Memar_0744 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator. | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.928 |
Mpal_2317 | fae-hps | Mpal_2317 | Mpal_1036 | KEGG: mbn:Mboo_0566 tetrahydromethanopterin S-methyltransferase subunit H; TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit. | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | 0.917 |
Mpal_2317 | ftr | Mpal_2317 | Mpal_2244 | KEGG: mbn:Mboo_0566 tetrahydromethanopterin S-methyltransferase subunit H; TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit. | Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. | 0.941 |
Mpal_2317 | mer | Mpal_2317 | Mpal_0327 | KEGG: mbn:Mboo_0566 tetrahydromethanopterin S-methyltransferase subunit H; TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit. | 5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. | 0.953 |
Mpal_2317 | mtd | Mpal_2317 | Mpal_0329 | KEGG: mbn:Mboo_0566 tetrahydromethanopterin S-methyltransferase subunit H; TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit. | Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. | 0.804 |
Mpal_2317 | mtrA | Mpal_2317 | Mpal_2314 | KEGG: mbn:Mboo_0566 tetrahydromethanopterin S-methyltransferase subunit H; TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit. | Tetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. | 0.999 |
Mpal_2317 | mtrC | Mpal_2317 | Mpal_2312 | KEGG: mbn:Mboo_0566 tetrahydromethanopterin S-methyltransferase subunit H; TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit. | Tetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. | 0.997 |
Mpal_2411 | Mpal_2121 | Mpal_2411 | Mpal_2121 | TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS); KEGG: mem:Memar_1507 sugar isomerase (SIS). | PFAM: Orotidine 5'-phosphate decarboxylase; Dimethylmenaquinone methyltransferase; KEGG: mem:Memar_0744 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator. | 0.996 |
Mpal_2411 | fae-hps | Mpal_2411 | Mpal_1036 | TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS); KEGG: mem:Memar_1507 sugar isomerase (SIS). | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | 0.995 |
Mpal_2411 | ftr | Mpal_2411 | Mpal_2244 | TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS); KEGG: mem:Memar_1507 sugar isomerase (SIS). | Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. | 0.613 |
Mpal_2411 | rpiA | Mpal_2411 | Mpal_0583 | TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS); KEGG: mem:Memar_1507 sugar isomerase (SIS). | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.569 |
fae-hps | Mpal_2121 | Mpal_1036 | Mpal_2121 | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | PFAM: Orotidine 5'-phosphate decarboxylase; Dimethylmenaquinone methyltransferase; KEGG: mem:Memar_0744 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator. | 0.934 |
fae-hps | Mpal_2317 | Mpal_1036 | Mpal_2317 | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | KEGG: mbn:Mboo_0566 tetrahydromethanopterin S-methyltransferase subunit H; TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit. | 0.917 |
fae-hps | Mpal_2411 | Mpal_1036 | Mpal_2411 | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | TIGRFAM: 6-phospho 3-hexuloisomerase; PFAM: sugar isomerase (SIS); KEGG: mem:Memar_1507 sugar isomerase (SIS). | 0.995 |
fae-hps | ftr | Mpal_1036 | Mpal_2244 | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | Formylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. | 0.985 |
fae-hps | glyA | Mpal_1036 | Mpal_0745 | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |
fae-hps | mer | Mpal_1036 | Mpal_0327 | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | 5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. | 0.913 |
fae-hps | mtd | Mpal_1036 | Mpal_0329 | Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily. | Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. | 0.938 |