STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apgMPhosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (411 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.926
pgk-2
PFAM: phosphoglycerate kinase; KEGG: mbn:Mboo_2342 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.921
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.919
Mpal_2019
KEGG: mem:Memar_0702 proposed homoserine kinase; TIGRFAM: phosphonopyruvate decarboxylase-related protein; proposed homoserine kinase; PFAM: metalloenzyme domain protein; Homoserine kinase family protein.
  
  
 
0.911
Mpal_0439
TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mbn:Mboo_2164 D-3-phosphoglycerate dehydrogenase.
    
 0.910
Mpal_0797
PFAM: protein of unknown function DUF100; KEGG: hbu:Hbut_0487 hypothetical protein.
 
  
 0.863
Mpal_1198
PFAM: glucose-6-phosphate isomerase; KEGG: mem:Memar_0485 glucose-6-phosphate isomerase.
     
 0.831
aroA-2
Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
     
 0.831
aroA-3
Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
     
 0.831
Mpal_0799
PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mma:MM_0714 aldolase.
     
 0.823
Your Current Organism:
Methanosphaerula palustris
NCBI taxonomy Id: 521011
Other names: Candidatus Methanosphaerula palustris E1-9c, M. palustris E1-9c, Methanosphaerula palustris E1-9c, Methanosphaerula palustris str. E1-9c, Methanosphaerula palustris strain E1-9c
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.