STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (253 aa)    
Predicted Functional Partners:
Kole_1113
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Peptidoglycan-binding LysM; SMART: Peptidoglycan-binding LysM; KEGG: sus:Acid_1294 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family.
    
 0.942
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.942
Kole_0818
PFAM: glutamine amidotransferase class-I; KEGG: cff:CFF8240_0351 anthranilate synthase component II.
    
 0.934
Kole_0291
AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)-like protein; KEGG: scl:sce3150 IMP cyclohydrolase.
     
 0.929
Kole_1770
TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: baa:BA_4387 competence-damaged protein; Belongs to the CinA family.
    
  0.923
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: geo:Geob_2362 cytidylate kinase.
    
 0.922
Kole_0384
KEGG: Phosphoribulokinase / Uridine kinase family protein.
  
  
 0.918
Kole_1573
Pyrimidine-nucleoside phosphorylase; KEGG: baa:BA_4765 glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like.
    
 0.918
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.917
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.916
Your Current Organism:
Kosmotoga olearia
NCBI taxonomy Id: 521045
Other names: K. olearia TBF 19.5.1, Kosmotoga olearia TBF 19.5.1, Thermotogales bacterium TBF 19.5.1
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