STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (323 aa)    
Predicted Functional Partners:
Kole_2137
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: dat:HRM2_41090 PorA2.
  
 
 0.969
Kole_0918
PFAM: Pyruvate kinase barrel; KEGG: hypothetical protein; K00873 pyruvate kinase.
  
 0.965
pykF
KEGG: bha:BH3163 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.965
Kole_0487
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: bar:GBAA4848 malate dehydrogenase, putative.
  
 0.948
Kole_1743
KEGG: glo:Glov_3566 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; Belongs to the PEP-utilizing enzyme family.
  
 
 0.935
Kole_0381
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: nam:NAMH_0242 pyruvate synthase subunit PorA.
  
 
 0.932
Kole_1740
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sfu:Sfum_1166 2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.932
Kole_2160
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sfu:Sfum_0301 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.932
Kole_0320
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: pca:Pcar_1029 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
  
 
 0.931
Kole_0382
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ppd:Ppro_0325 thiamine pyrophosphate binding domain-containing protein.
  
 
 0.931
Your Current Organism:
Kosmotoga olearia
NCBI taxonomy Id: 521045
Other names: K. olearia TBF 19.5.1, Kosmotoga olearia TBF 19.5.1, Thermotogales bacterium TBF 19.5.1
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