STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aaci_0749PFAM: Aldehyde Dehydrogenase; KEGG: pat:Patl_3760 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa)    
Predicted Functional Partners:
Aaci_0445
PFAM: AMP-dependent synthetase and ligase; KEGG: rhi:NGR_c26750 acetyl-CoA synthetase.
  
 0.927
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.927
Aaci_1456
PFAM: AMP-dependent synthetase and ligase; KEGG: dal:Dalk_0007 AMP-dependent synthetase and ligase.
  
 0.927
Aaci_0315
KEGG: rme:Rmet_1618 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.924
Aaci_2081
KEGG: gur:Gura_0119 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.924
Aaci_1454
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: ank:AnaeK_1629 methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.920
Aaci_0886
PFAM: CoA-binding domain protein; KEGG: dol:Dole_3063 CoA-binding domain-containing protein.
    
 0.918
Aaci_0920
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: sme:SMc03929 putative zinc-type alcohol dehydrogenase transmembrane protein.
 
 0.918
iolA
Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
  
  
 
0.917
Aaci_0152
PFAM: Aldehyde Dehydrogenase; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.914
Your Current Organism:
Alicyclobacillus acidocaldarius DSM 446
NCBI taxonomy Id: 521098
Other names: A. acidocaldarius subsp. acidocaldarius DSM 446, Alicyclobacillus acidocaldarius subsp. acidocaldarius ATCC 27009, Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446, Alicyclobacillus acidocaldarius subsp. acidocaldarius IFO 15652, Alicyclobacillus acidocaldarius subsp. acidocaldarius JCM 5260, Alicyclobacillus acidocaldarius subsp. acidocaldarius NBRC 15652, Alicyclobacillus acidocaldarius subsp. acidocaldarius NCIB 11725, Alicyclobacillus acidocaldarius subsp. acidocaldarius str. DSM 446, Alicyclobacillus acidocaldarius subsp. acidocaldarius strain DSM 446
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