node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aaci_0450 | Aaci_0733 | Aaci_0450 | Aaci_0733 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.444 |
Aaci_0450 | Aaci_0916 | Aaci_0450 | Aaci_0916 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.941 |
Aaci_0450 | Aaci_1226 | Aaci_0450 | Aaci_1226 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamine amidotransferase class-II; KEGG: gur:Gura_0393 glutamate synthase (ferredoxin). | 0.909 |
Aaci_0450 | Aaci_1313 | Aaci_0450 | Aaci_1313 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: nmc:NMC1413 putative glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.819 |
Aaci_0450 | Aaci_1557 | Aaci_0450 | Aaci_1557 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | KEGG: hypothetical protein; K00031 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.910 |
Aaci_0450 | Aaci_1711 | Aaci_0450 | Aaci_1711 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: sfu:Sfum_3265 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.819 |
Aaci_0450 | Aaci_2144 | Aaci_0450 | Aaci_2144 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | 2-oxoglutarate dehydrogenase, E1 subunit; KEGG: sfu:Sfum_3547 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region. | 0.919 |
Aaci_0450 | Aaci_2348 | Aaci_0450 | Aaci_2348 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | KEGG: afw:Anae109_2186 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.954 |
Aaci_0450 | sucC | Aaci_0450 | Aaci_1375 | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.452 |
Aaci_0733 | Aaci_0450 | Aaci_0733 | Aaci_0450 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | 0.444 |
Aaci_0733 | Aaci_0916 | Aaci_0733 | Aaci_0916 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.627 |
Aaci_0733 | Aaci_1557 | Aaci_0733 | Aaci_1557 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | KEGG: hypothetical protein; K00031 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.444 |
Aaci_0733 | Aaci_2144 | Aaci_0733 | Aaci_2144 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 2-oxoglutarate dehydrogenase, E1 subunit; KEGG: sfu:Sfum_3547 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region. | 0.730 |
Aaci_0733 | Aaci_2348 | Aaci_0733 | Aaci_2348 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | KEGG: afw:Anae109_2186 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.965 |
Aaci_0733 | mdh | Aaci_0733 | Aaci_2347 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.991 |
Aaci_0733 | sucC | Aaci_0733 | Aaci_1375 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.632 |
Aaci_0916 | Aaci_0450 | Aaci_0916 | Aaci_0450 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pca:Pcar_0575 isocitrate/isopropylmalate dehydrogenase. | 0.941 |
Aaci_0916 | Aaci_0733 | Aaci_0916 | Aaci_0733 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.627 |
Aaci_0916 | Aaci_1226 | Aaci_0916 | Aaci_1226 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamine amidotransferase class-II; KEGG: gur:Gura_0393 glutamate synthase (ferredoxin). | 0.592 |
Aaci_0916 | Aaci_1557 | Aaci_0916 | Aaci_1557 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | KEGG: hypothetical protein; K00031 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. | 0.951 |