node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Athe_1289 | Athe_1335 | Athe_1289 | Athe_1335 | KEGG: csc:Csac_1854 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.452 |
Athe_1289 | argR | Athe_1289 | Athe_1334 | KEGG: csc:Csac_1854 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein. | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. | 0.503 |
Athe_1289 | dxs | Athe_1289 | Athe_1288 | KEGG: csc:Csac_1854 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.915 |
Athe_1289 | ispH | Athe_1289 | Athe_1327 | KEGG: csc:Csac_1854 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.447 |
Athe_1289 | nadK | Athe_1289 | Athe_1333 | KEGG: csc:Csac_1854 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.711 |
Athe_1332 | Athe_1335 | Athe_1332 | Athe_1335 | PFAM: histidine triad (HIT) protein; KEGG: csc:Csac_1895 histidine triad (HIT) protein. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.575 |
Athe_1332 | Athe_1336 | Athe_1332 | Athe_1336 | PFAM: histidine triad (HIT) protein; KEGG: csc:Csac_1895 histidine triad (HIT) protein. | TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; KEGG: csc:Csac_1899 peptidase S55, SpoIVB. | 0.423 |
Athe_1332 | alaS | Athe_1332 | Athe_1331 | PFAM: histidine triad (HIT) protein; KEGG: csc:Csac_1895 histidine triad (HIT) protein. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.847 |
Athe_1332 | argR | Athe_1332 | Athe_1334 | PFAM: histidine triad (HIT) protein; KEGG: csc:Csac_1895 histidine triad (HIT) protein. | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. | 0.559 |
Athe_1332 | ispH | Athe_1332 | Athe_1327 | PFAM: histidine triad (HIT) protein; KEGG: csc:Csac_1895 histidine triad (HIT) protein. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.573 |
Athe_1332 | nadK | Athe_1332 | Athe_1333 | PFAM: histidine triad (HIT) protein; KEGG: csc:Csac_1895 histidine triad (HIT) protein. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.643 |
Athe_1335 | Athe_1289 | Athe_1335 | Athe_1289 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | KEGG: csc:Csac_1854 hemolysin A; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein. | 0.452 |
Athe_1335 | Athe_1332 | Athe_1335 | Athe_1332 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | PFAM: histidine triad (HIT) protein; KEGG: csc:Csac_1895 histidine triad (HIT) protein. | 0.575 |
Athe_1335 | Athe_1336 | Athe_1335 | Athe_1336 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; KEGG: csc:Csac_1899 peptidase S55, SpoIVB. | 0.703 |
Athe_1335 | alaS | Athe_1335 | Athe_1331 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.567 |
Athe_1335 | argR | Athe_1335 | Athe_1334 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. | 0.886 |
Athe_1335 | dxs | Athe_1335 | Athe_1288 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.487 |
Athe_1335 | ispH | Athe_1335 | Athe_1327 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.521 |
Athe_1335 | nadK | Athe_1335 | Athe_1333 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.842 |
Athe_1336 | Athe_1332 | Athe_1336 | Athe_1332 | TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; KEGG: csc:Csac_1899 peptidase S55, SpoIVB. | PFAM: histidine triad (HIT) protein; KEGG: csc:Csac_1895 histidine triad (HIT) protein. | 0.423 |