STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (915 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.920
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.918
Plim_2420
KEGG: sfu:Sfum_2562 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate- binding; PEP-utilising protein mobile region; PEP- utilizing protein; Belongs to the PEP-utilizing enzyme family.
     
 0.918
Plim_3274
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.918
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.913
Plim_2694
Glutamate synthase (NADH).
  
  
 0.871
Plim_0895
KEGG: bha:BH3160 methylcitrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
     
 0.829
Plim_3053
4Fe-4S ferredoxin iron-sulfur binding domain protein.
     
 0.826
Plim_0191
PFAM: formyl transferase domain protein; KEGG: csa:Csal_2073 formyltetrahydrofolate deformylase.
     
  0.800
Plim_0678
Ammonium transporter; KEGG: pla:Plav_1427 integral membrane sensor signal transduction histidine kinase; TIGRFAM: ammonium transporter; PAS sensor protein; PFAM: Rh family protein/ammonium transporter; ATP- binding region ATPase domain protein; Hpt domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain containing protein.
  
  
 0.499
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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