STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV37320.1PFAM: ATP dependent DNA ligase; KEGG: dar:Daro_1235 DNA ligase. (280 aa)    
Predicted Functional Partners:
ACV33377.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.978
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.975
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
    
 0.932
ACV35758.1
TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: dar:Daro_2196 DNA polymerase III, delta prime subunit.
   
 0.871
ACV36954.1
TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Polynucleotide kinase 3 phosphatase central region; KEGG: dar:Daro_3536 D,D-heptose 1,7-bisphosphate phosphatase.
   
 0.859
ACV36374.1
PFAM: metallophosphoesterase; KEGG: lch:Lcho_1563 metallophosphoesterase.
  
 0.839
ACV36540.1
SMART: helicase c2; KEGG: dar:Daro_1779 helicase c2:DEAD/DEAH box helicase, N-terminal.
   
 
 0.824
ACV34032.1
Exodeoxyribonuclease III Xth; KEGG: dar:Daro_0123 AP endonuclease, family 1:exodeoxyribonuclease III xth; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
  
 
 0.816
ACV34158.1
TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: dar:Daro_3648 exodeoxyribonuclease III.
  
 
 0.816
ACV34863.1
KEGG: dar:Daro_2027 Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; Belongs to the peptidase S26 family.
    
 0.782
Your Current Organism:
Accumulibacter phosphatis
NCBI taxonomy Id: 522306
Other names: Accumulibacter phosphatis UW-1, C. Accumulibacter phosphatis clade IIA str. UW-1, Candidatus Accumulibacter phosphatis Type IIA str. UW-1, Candidatus Accumulibacter phosphatis clade IIA str. UW-1, Candidatus Accumulibacter phosphatis clade IIA strain UW-1
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