STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACV37600.1Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. (402 aa)    
Predicted Functional Partners:
ACV37601.1
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
 
 0.999
ACV35318.1
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 0.993
ACV37374.1
PFAM: SirA family protein; KEGG: dar:Daro_3088 SirA-like; Belongs to the sulfur carrier protein TusA family.
   
 0.979
ACV37610.1
PFAM: NifQ family protein; KEGG: bxe:Bxe_B1476 putative nitrogen fixation-related protein(NifQ).
 
 0.954
ACV34816.1
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: azo:azo2804 adenylyltransferase, putative.
   
 0.952
cyaY
Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
   
 0.950
ACV37343.1
PFAM: Rhodanese domain protein; KEGG: azo:azo2754 putative thiosulfate sulfurtransferase.
  
 0.921
ACV35316.1
PFAM: aminotransferase class V; KEGG: dar:Daro_1949 aminotransferase, class V.
  
  
 
0.909
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
  
 
0.908
ACV37602.1
TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: dar:Daro_1513 HesB/YadR/YfhF; Belongs to the HesB/IscA family.
 
  
 0.875
Your Current Organism:
Accumulibacter phosphatis
NCBI taxonomy Id: 522306
Other names: Accumulibacter phosphatis UW-1, C. Accumulibacter phosphatis clade IIA str. UW-1, Candidatus Accumulibacter phosphatis Type IIA str. UW-1, Candidatus Accumulibacter phosphatis clade IIA str. UW-1, Candidatus Accumulibacter phosphatis clade IIA strain UW-1
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