STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
lspALipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family (174 aa)    
Predicted Functional Partners:
Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis; Belongs to the IspH family
Riboflavin biosynthesis protein; Similarity:fasta; with=UniProt:P0AG40 (EMBL:M10428;); Escherichia coli; ribF; Riboflavin biosynthesis protein ribF [Includes: Riboflavin kinase (EC (Flavokinase); FMN adenylyltransferase (EC (FAD pyrophosphorylase) (FAD synthetase)].; length=313; id 45.395%; ungapped id 46.000%; E()=8.3e-42; 304 aa overlap; query 3-303; subject 2-304; similarity:fasta; with=UniProt:Q8PN20 (EMBL:AE011755;); Xanthomonas axonopodis pv. citri.; ribF; Riboflavin biosynthesis protein.; length=340; id 77.346%; ungapped id 77.346%; E()=2.3e-90; 309 aa overlap [...]
Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
Signal peptidase I; Similarity:fasta; CAL2866; bcenocepacia; signal peptidase I; length 297 aa; id=43.7%; E()=7.1e-24; 247 aa overlap; query 22-244 aa; subject 48-286 aa; similarity:fasta; BPP3296; bparapertussis; signal peptidase I; length 294 aa; id=37.9%; E()=1.6e-20; 285 aa overlap; query 4-244 aa; subject 5-283 aa; similarity:fasta; BB3747; bbronchiseptica; signal peptidase I; length 294 aa; id=37.7%; E()=1.7e-20; 289 aa overlap; query 4-244 aa; subject 5-283 aa; Belongs to the peptidase S26 family
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily
Prolipoprotein diacylglyceryl transferase; Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate; In the C-terminal section; belongs to the HTP reductase family
Putative transmembrane protein; Similarity:fasta; with=UniProt:Q8PCS6; Xanthomonas campestris pv. campestris; Hypothetical protein XCC0636.; length=419; id 75.238%; ungapped id 75.598%; E()=6.3e-116; 420 aa overlap; query 1-419; subject 1-419
Your Current Organism:
Stenotrophomonas maltophilia K279a
NCBI taxonomy Id: 522373
Other names: S. maltophilia K279a, Stenotrophomonas maltophilia K279a, Stenotrophomonas maltophilia str. K279a, Stenotrophomonas maltophilia strain K279a
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