node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HFX_1513 | accA2 | HFX_1513 | HFX_2490 | propionyl-CoA carboxylase carboxyltransferase component. | Biotin carboxylase; This is one of the subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase is involved in propionate utilization and in the production of the poly(3-hyd [...] | 0.992 |
HFX_1513 | birA | HFX_1513 | HFX_2489 | propionyl-CoA carboxylase carboxyltransferase component. | Bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | 0.724 |
HFX_1513 | leuA2 | HFX_1513 | HFX_1573 | propionyl-CoA carboxylase carboxyltransferase component. | 2-isopropylmalate synthase 2; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.512 |
HFX_1513 | paaJ | HFX_1513 | HFX_0804 | propionyl-CoA carboxylase carboxyltransferase component. | acetyl-CoA C-acyltransferase. | 0.439 |
HFX_1513 | paaJ-2 | HFX_1513 | HFX_2006 | propionyl-CoA carboxylase carboxyltransferase component. | acetyl-CoA C-ac(et)yltransferase. | 0.434 |
HFX_1513 | pccX | HFX_1513 | HFX_2479 | propionyl-CoA carboxylase carboxyltransferase component. | Hypothetical protein; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. PccX could be responsible for the interaction of the biotin carboxylase and carboxyltransferase subunits. | 0.643 |
HFX_1513 | phaAa | HFX_1513 | HFX_1023 | propionyl-CoA carboxylase carboxyltransferase component. | PHA-specific beta-ketothiolase alpha subunit. | 0.439 |
accA | accA2 | HFX_2478 | HFX_2490 | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | Biotin carboxylase; This is one of the subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase is involved in propionate utilization and in the production of the poly(3-hyd [...] | 0.999 |
accA | acs | HFX_2478 | HFX_0870 | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | acyl-CoA synthetase. | 0.922 |
accA | birA | HFX_2478 | HFX_2489 | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | Bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | 0.726 |
accA | leuA2 | HFX_2478 | HFX_1573 | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | 2-isopropylmalate synthase 2; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.898 |
accA | paaJ | HFX_2478 | HFX_0804 | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | acetyl-CoA C-acyltransferase. | 0.941 |
accA | paaJ-2 | HFX_2478 | HFX_2006 | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | acetyl-CoA C-ac(et)yltransferase. | 0.941 |
accA | pccX | HFX_2478 | HFX_2479 | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | Hypothetical protein; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. PccX could be responsible for the interaction of the biotin carboxylase and carboxyltransferase subunits. | 0.995 |
accA | pdhC | HFX_2478 | HFX_2954 | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | Dihydrolipoamide S-acyltransferase (pyruvate dehydrogenase E2 component). | 0.862 |
accA | phaAa | HFX_2478 | HFX_1023 | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | PHA-specific beta-ketothiolase alpha subunit. | 0.941 |
accA2 | HFX_1513 | HFX_2490 | HFX_1513 | Biotin carboxylase; This is one of the subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase is involved in propionate utilization and in the production of the poly(3-hyd [...] | propionyl-CoA carboxylase carboxyltransferase component. | 0.992 |
accA2 | accA | HFX_2490 | HFX_2478 | Biotin carboxylase; This is one of the subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase is involved in propionate utilization and in the production of the poly(3-hyd [...] | methylmalonyl-CoA decarboxylase alpha chain; Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3- hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation. The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA. PCC is also able to catalyze the carboxylation of acetyl-CoA. | 0.999 |
accA2 | acs | HFX_2490 | HFX_0870 | Biotin carboxylase; This is one of the subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase is involved in propionate utilization and in the production of the poly(3-hyd [...] | acyl-CoA synthetase. | 0.925 |
accA2 | birA | HFX_2490 | HFX_2489 | Biotin carboxylase; This is one of the subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase is involved in propionate utilization and in the production of the poly(3-hyd [...] | Bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | 0.987 |