STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mfer_0346COGs: COG4007 dehydrogenase related to H2-forming N5 N10-methylenetetrahydromethanopterin dehydrogenase; InterPro IPR010063: IPR016040: IPR004889; KEGG: mfe:Mefer_0170 coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein; PFAM: H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase; SPTR: C7P627 Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein; TIGRFAM: coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein; PFAM: NAD binding domain of 6-phosphogluconate d [...] (336 aa)    
Predicted Functional Partners:
Mfer_0347
KEGG: conserved hypothetical protein; SPTR: Q8I5W3 Conserved Plasmodium protein.
       0.752
Mfer_0345
CobB/CobQ domain protein glutamine amidotransferase; COGs: COG1492 Cobyric acid synthase; InterPro IPR017929: IPR011698; KEGG: mth:MTH1497 cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: O27541 Cobyrinic acid a,c-diamide synthase related protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain.
       0.737
Mfer_0348
KEGG: rsk:RSKD131_2258 ammonium transporter precursor; SPTR: C5RNC0 Ammonium transporter.
       0.682
Mfer_0303
Roadblock/LC7 family protein; COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: mth:MTH1836 hypothetical protein; PFAM: Roadblock/LC7 family protein; SPTR: O27864 Conserved protein; PFAM: Roadblock/LC7 domain.
  
    0.644
Mfer_0948
Roadblock/LC7 family protein; COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: mth:MTH1836 hypothetical protein; PFAM: Roadblock/LC7 family protein; SPTR: O27864 Conserved protein; PFAM: Roadblock/LC7 domain.
  
    0.644
Mfer_0349
KEGG: mth:MTH969 hypothetical protein; SPTR: O27050 Putative uncharacterized protein.
       0.460
Your Current Organism:
Methanothermus fervidus
NCBI taxonomy Id: 523846
Other names: M. fervidus DSM 2088, Methanothermus fervidus ATCC 43054, Methanothermus fervidus DSM 2088, Methanothermus fervidus V24S, Methanothermus fervidus str. DSM 2088, Methanothermus fervidus strain DSM 2088
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.