STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gyaRGlyoxylate reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily. (331 aa)    
Predicted Functional Partners:
OCC_03432
Glycerate kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 0.956
OCC_09988
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.920
OCC_08355
2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.906
OCC_02240
Alanine glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
    0.634
OCC_05164
Peptidase U34; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
    0.537
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.431
OCC_11879
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 0.428
gpmA
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
 
  
 0.427
pki
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the pyruvate kinase family.
  
 
 0.417
malP
Alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Catalyzes the phospholytic cleavage of maltodextrins with a minmal chain length of five glucose residues to yield glucose-1-phosphate. Low activity with tetraose and no activity with triose and maltose. Long maltodextrins (8 to 15 glucose units), amylose and starch are not as good substrates as maltoheptaose.
  
  
 0.417
Your Current Organism:
Thermococcus litoralis
NCBI taxonomy Id: 523849
Other names: T. litoralis DSM 5473, Thermococcus litoralis ATCC 51850, Thermococcus litoralis DSM 5473, Thermococcus litoralis JCM 8560, Thermococcus litoralis NS-C, Thermococcus litoralis str. DSM 5473, Thermococcus litoralis strain DSM 5473
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