STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (223 aa)    
Predicted Functional Partners:
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
  
 0.987
gpsA
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: dvl:Dvul_0226 glycerol-3-phosphate dehydrogenase (NAD(P)(+)).
 
 
 0.953
Ddes_1167
PFAM: phospholipid/glycerol acyltransferase; KEGG: dvl:Dvul_1399 phospholipid/glycerol acyltransferase.
  
 
 0.944
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
    
 0.914
Ddes_1521
TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: drm:Dred_2844 FAD dependent oxidoreductase.
     
 0.913
Ddes_1519
TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: lip:LI1084 sn-glycerol-3-phosphate dehydrogenase subunit C.
     
  0.900
Ddes_1520
KEGG: lip:LI1085 anaerobic glycerol-3-phosphate dehydrogenase subunit B; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.
     
  0.900
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.733
Ddes_2061
PFAM: Acyl transferase; KEGG: sco:SCO5892 polyketide synthase.
     
 0.645
Ddes_0103
PFAM: ribonuclease II; KEGG: dvl:Dvul_0179 ribonuclease II.
       0.561
Your Current Organism:
Desulfovibrio desulfuricans ATCC 27774
NCBI taxonomy Id: 525146
Other names: D. desulfuricans ATCC 27774, Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774
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