STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (316 aa)    
Predicted Functional Partners:
bioD
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
 0.992
Ddes_1554
TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: dvl:Dvul_1327 biotin--acetyl-CoA-carboxylase ligase.
  
 
 0.917
Ddes_1504
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: dvu:DVU1767 biotin synthase.
     
  0.900
Ddes_2059
Glycine C-acetyltransferase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: neu:NE1388 aminotransferase class-I.
  
 0.857
bioW
6-carboxyhexanoate--CoA ligase; Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
 
  
 0.734
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
 0.714
Ddes_0218
PFAM: aminotransferase class-III; KEGG: pin:Ping_0051 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.609
Ddes_0628
PFAM: thiamine biosynthesis protein ThiC; KEGG: dvl:Dvul_1663 thiamine biosynthesis protein ThiC.
 
  
 0.523
Ddes_1076
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
   
 
 0.483
Ddes_1619
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.444
Your Current Organism:
Desulfovibrio desulfuricans ATCC 27774
NCBI taxonomy Id: 525146
Other names: D. desulfuricans ATCC 27774, Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774
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