STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (212 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.999
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
 0.999
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.994
pyrB
Aspartate carbamoyltransferase; COG: COG0540; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.992
EEJ72538.1
Putative permease; COG: COG2233.
  
  
 0.969
carB
Carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family.
  
 
 0.968
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.968
EEJ73045.1
Putative carbamoyl-phosphate synthase, large subunit; COG: COG0458; Belongs to the CarB family.
  
 
 0.960
prs
Ribose-phosphate diphosphokinase; COG: COG0462.
  
 
 0.948
prs-2
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.948
Your Current Organism:
Lactobacillus ultunensis
NCBI taxonomy Id: 525365
Other names: L. ultunensis DSM 16047, Lactobacillus ultunensis DSM 16047, Lactobacillus ultunensis str. DSM 16047, Lactobacillus ultunensis strain DSM 16047
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.