STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EV44_g4603S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (386 aa)    
Predicted Functional Partners:
EV44_g0619
Putative substrate binding domain-containing protein.
   
 0.993
EV44_g4525
Putative 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
  
 0.977
EV44_g6397
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.943
EV44_g5106
Histidine biosynthesis trifunctional protein.
  
 
 0.912
EV44_g3009
Putative nad dependent epimerase dehydratase family protein.
   
 0.900
EV44_g2514
Putative sterol-4-alpha-carboxylate 3-dehydrogenase like protein.
   
 0.900
EV44_g4716
Putative spermidine synthase; Belongs to the spermidine/spermine synthase family.
  
 
 0.894
EV44_g6370
Putative homocysteine s-methyltransferase.
  
 
 0.879
EV44_g1492
Adenosylhomocysteinase.
  
 
 0.878
EV44_g1618
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.866
Your Current Organism:
Erysiphe necator
NCBI taxonomy Id: 52586
Other names: E. necator, Uncinula necator, grape powdery mildew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.