STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EV44_g1639Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family. (535 aa)    
Predicted Functional Partners:
EV44_g5292
Putative importin beta-1 subunit.
    
   0.977
EV44_g2660
Importin subunit alpha; Belongs to the importin alpha family.
    
   0.977
EV44_g2229
Putative pumilio domain-containing protein.
   
 
 0.938
EV44_g1803
Putative brix domain-containing protein.
   
   0.935
EV44_g2401
Putative constituent of 66s pre-ribosomal particles.
   
   0.934
EV44_g0930
Putative ribosomal processing rna binding nucleolar protein.
   
   0.931
EV44_g4678
Putative ribosome biogenesis protein brx1.
   
   0.929
EV44_g2482
Putative rrna processing protein ebp2.
   
   0.925
EV44_g4720
Putative rrna processing protein bystin.
   
 
 0.915
EV44_g0941
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
   0.915
Your Current Organism:
Erysiphe necator
NCBI taxonomy Id: 52586
Other names: E. necator, Uncinula necator, grape powdery mildew
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