node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sdel_0004 | glmM | Sdel_0004 | Sdel_0078 | DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | 0.793 |
Sdel_0044 | Sdel_1791 | Sdel_0044 | Sdel_1791 | UTP-glucose-1-phosphate uridylyltransferase | Mannose-1-phosphate guanylyltransferase/mannose- 6-phosphate isomerase | 0.614 |
Sdel_0044 | glmM | Sdel_0044 | Sdel_0078 | UTP-glucose-1-phosphate uridylyltransferase | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | 0.769 |
Sdel_0044 | glmS | Sdel_0044 | Sdel_1689 | UTP-glucose-1-phosphate uridylyltransferase | Glucosamine/fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source | 0.536 |
Sdel_0044 | glmU | Sdel_0044 | Sdel_1123 | UTP-glucose-1-phosphate uridylyltransferase | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | 0.587 |
Sdel_0492 | glmM | Sdel_0492 | Sdel_0078 | UDP-N-acetylmuramate/alanine ligase; Cell wall formation | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | 0.792 |
Sdel_0492 | glmU | Sdel_0492 | Sdel_1123 | UDP-N-acetylmuramate/alanine ligase; Cell wall formation | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | 0.817 |
Sdel_0492 | murB | Sdel_0492 | Sdel_2239 | UDP-N-acetylmuramate/alanine ligase; Cell wall formation | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation | 0.998 |
Sdel_1374 | glmM | Sdel_1374 | Sdel_0078 | Dihydropteroate synthase | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | 0.877 |
Sdel_1374 | tpiA | Sdel_1374 | Sdel_0423 | Dihydropteroate synthase | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) | 0.514 |
Sdel_1791 | Sdel_0044 | Sdel_1791 | Sdel_0044 | Mannose-1-phosphate guanylyltransferase/mannose- 6-phosphate isomerase | UTP-glucose-1-phosphate uridylyltransferase | 0.614 |
Sdel_1791 | glmM | Sdel_1791 | Sdel_0078 | Mannose-1-phosphate guanylyltransferase/mannose- 6-phosphate isomerase | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | 0.966 |
Sdel_1791 | glmS | Sdel_1791 | Sdel_1689 | Mannose-1-phosphate guanylyltransferase/mannose- 6-phosphate isomerase | Glucosamine/fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source | 0.496 |
glmM | Sdel_0004 | Sdel_0078 | Sdel_0004 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA | 0.793 |
glmM | Sdel_0044 | Sdel_0078 | Sdel_0044 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | UTP-glucose-1-phosphate uridylyltransferase | 0.769 |
glmM | Sdel_0492 | Sdel_0078 | Sdel_0492 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | UDP-N-acetylmuramate/alanine ligase; Cell wall formation | 0.792 |
glmM | Sdel_1374 | Sdel_0078 | Sdel_1374 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | Dihydropteroate synthase | 0.877 |
glmM | Sdel_1791 | Sdel_0078 | Sdel_1791 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | Mannose-1-phosphate guanylyltransferase/mannose- 6-phosphate isomerase | 0.966 |
glmM | glmS | Sdel_0078 | Sdel_1689 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | Glucosamine/fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source | 0.990 |
glmM | glmU | Sdel_0078 | Sdel_1123 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | 0.994 |