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nfo protein (Sulfurospirillum deleyianum) - STRING interaction network
"nfo" - Apurinic endonuclease Apn1 in Sulfurospirillum deleyianum
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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nfoApurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5’-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (280 aa)    
Predicted Functional Partners:
Sdel_0133
Hypothetical protein (161 aa)
              0.868
Sdel_0132
Ferric-uptake regulator (123 aa)
              0.834
Sdel_0135
Aromatic hydrocarbon degradation membrane protein (405 aa)
              0.823
Sdel_0558
DNA polymerase I (885 aa)
     
 
  0.818
Sdel_0136
AMP-dependent synthetase and ligase (520 aa)
              0.815
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (213 aa)
   
 
  0.711
Sdel_0010
A/G-specific adenine glycosylase (317 aa)
     
   
  0.681
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] (694 aa)
   
 
  0.658
Sdel_0131
Periplasmic solute binding protein (285 aa)
              0.610
Sdel_0130
ABC transporter (253 aa)
              0.595
Your Current Organism:
Sulfurospirillum deleyianum
NCBI taxonomy Id: 525898
Other names: Dehalospirillum, Dehalospirillum Scholz-Muramatsu et al. 2002, Geospirillum, S. deleyianum, S. deleyianum DSM 6946, Sulfurospirillum, Sulfurospirillum deleyianum, Sulfurospirillum deleyianum DSM 6946, Sulfurospirillum deleyianum str. DSM 6946, Sulfurospirillum deleyianum strain DSM 6946
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