node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sdel_0501 | Sdel_0604 | Sdel_0501 | Sdel_0604 | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cco:CCC13826_1508 glyceraldehyde-3-phosphate dehydrogenase 2. | 0.947 |
Sdel_0501 | Sdel_1295 | Sdel_0501 | Sdel_1295 | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. | 0.800 |
Sdel_0501 | Sdel_2195 | Sdel_0501 | Sdel_2195 | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | Malate dehydrogenase (oxaloacetate- decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: ccv:CCV52592_0547 malic enzyme NAD binding subunit. | 0.953 |
Sdel_0501 | ilvD | Sdel_0501 | Sdel_0041 | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | KEGG: cco:CCC13826_0012 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.524 |
Sdel_0501 | leuA | Sdel_0501 | Sdel_1758 | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.826 |
Sdel_0501 | leuC | Sdel_0501 | Sdel_2259 | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.817 |
Sdel_0501 | leuD | Sdel_0501 | Sdel_1517 | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.816 |
Sdel_0604 | Sdel_0501 | Sdel_0604 | Sdel_0501 | PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cco:CCC13826_1508 glyceraldehyde-3-phosphate dehydrogenase 2. | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.947 |
Sdel_0604 | Sdel_1295 | Sdel_0604 | Sdel_1295 | PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cco:CCC13826_1508 glyceraldehyde-3-phosphate dehydrogenase 2. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. | 0.801 |
Sdel_0604 | Sdel_2195 | Sdel_0604 | Sdel_2195 | PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cco:CCC13826_1508 glyceraldehyde-3-phosphate dehydrogenase 2. | Malate dehydrogenase (oxaloacetate- decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: ccv:CCV52592_0547 malic enzyme NAD binding subunit. | 0.937 |
Sdel_0604 | leuA | Sdel_0604 | Sdel_1758 | PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cco:CCC13826_1508 glyceraldehyde-3-phosphate dehydrogenase 2. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.831 |
Sdel_0604 | leuC | Sdel_0604 | Sdel_2259 | PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cco:CCC13826_1508 glyceraldehyde-3-phosphate dehydrogenase 2. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.805 |
Sdel_0604 | leuD | Sdel_0604 | Sdel_1517 | PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cco:CCC13826_1508 glyceraldehyde-3-phosphate dehydrogenase 2. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.868 |
Sdel_1295 | Sdel_0501 | Sdel_1295 | Sdel_0501 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. | Pyruvate kinase; KEGG: cff:CFF8240_0630 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. | 0.800 |
Sdel_1295 | Sdel_0604 | Sdel_1295 | Sdel_0604 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. | PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cco:CCC13826_1508 glyceraldehyde-3-phosphate dehydrogenase 2. | 0.801 |
Sdel_1295 | Sdel_1352 | Sdel_1295 | Sdel_1352 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. | KEGG: abu:Abu_2067 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.658 |
Sdel_1295 | Sdel_2195 | Sdel_1295 | Sdel_2195 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. | Malate dehydrogenase (oxaloacetate- decarboxylating) (NADP(+)); PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: ccv:CCV52592_0547 malic enzyme NAD binding subunit. | 0.822 |
Sdel_1295 | ilvC | Sdel_1295 | Sdel_0867 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.997 |
Sdel_1295 | ilvD | Sdel_1295 | Sdel_0041 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. | KEGG: cco:CCC13826_0012 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.917 |
Sdel_1295 | leuA | Sdel_1295 | Sdel_1758 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: ccv:CCV52592_1429 acetolactate synthase 3 regulatory subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.957 |