node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS78113.1 | ACS78114.1 | Desal_0041 | Desal_0042 | KEGG: dde:Dde_0540 phenylacetate-coenzyme A ligase, putative. | PFAM: protein of unknown function DUF399; KEGG: dde:Dde_0541 PDZ/DHR/GLGF. | 0.806 |
ACS78113.1 | mutM | Desal_0041 | Desal_0043 | KEGG: dde:Dde_0540 phenylacetate-coenzyme A ligase, putative. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.750 |
ACS78114.1 | ACS78113.1 | Desal_0042 | Desal_0041 | PFAM: protein of unknown function DUF399; KEGG: dde:Dde_0541 PDZ/DHR/GLGF. | KEGG: dde:Dde_0540 phenylacetate-coenzyme A ligase, putative. | 0.806 |
ACS78114.1 | mutM | Desal_0042 | Desal_0043 | PFAM: protein of unknown function DUF399; KEGG: dde:Dde_0541 PDZ/DHR/GLGF. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.798 |
ACS79726.1 | mutM | Desal_1664 | Desal_0043 | KEGG: geo:Geob_2863 hypothetical protein. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.625 |
ACS79726.1 | polA | Desal_1664 | Desal_2961 | KEGG: geo:Geob_2863 hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.527 |
ACS80355.1 | coaE | Desal_2299 | Desal_1576 | PFAM: NUDIX hydrolase; KEGG: dvm:DvMF_2380 NUDIX hydrolase; Belongs to the Nudix hydrolase family. | Pseudouridine synthase, RluA family; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.636 |
ACS80355.1 | mutM | Desal_2299 | Desal_0043 | PFAM: NUDIX hydrolase; KEGG: dvm:DvMF_2380 NUDIX hydrolase; Belongs to the Nudix hydrolase family. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.559 |
ACS80355.1 | polA | Desal_2299 | Desal_2961 | PFAM: NUDIX hydrolase; KEGG: dvm:DvMF_2380 NUDIX hydrolase; Belongs to the Nudix hydrolase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.427 |
ACS80355.1 | recA | Desal_2299 | Desal_3121 | PFAM: NUDIX hydrolase; KEGG: dvm:DvMF_2380 NUDIX hydrolase; Belongs to the Nudix hydrolase family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.467 |
ACS80785.1 | mutM | Desal_2731 | Desal_0043 | KEGG: geo:Geob_2863 hypothetical protein. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.625 |
ACS80785.1 | polA | Desal_2731 | Desal_2961 | KEGG: geo:Geob_2863 hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.527 |
coaE | ACS80355.1 | Desal_1576 | Desal_2299 | Pseudouridine synthase, RluA family; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | PFAM: NUDIX hydrolase; KEGG: dvm:DvMF_2380 NUDIX hydrolase; Belongs to the Nudix hydrolase family. | 0.636 |
coaE | mutM | Desal_1576 | Desal_0043 | Pseudouridine synthase, RluA family; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.898 |
coaE | nth | Desal_1576 | Desal_2504 | Pseudouridine synthase, RluA family; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.619 |
coaE | polA | Desal_1576 | Desal_2961 | Pseudouridine synthase, RluA family; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.882 |
coaE | recA | Desal_1576 | Desal_3121 | Pseudouridine synthase, RluA family; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.550 |
mutM | ACS78113.1 | Desal_0043 | Desal_0041 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | KEGG: dde:Dde_0540 phenylacetate-coenzyme A ligase, putative. | 0.750 |
mutM | ACS78114.1 | Desal_0043 | Desal_0042 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | PFAM: protein of unknown function DUF399; KEGG: dde:Dde_0541 PDZ/DHR/GLGF. | 0.798 |
mutM | ACS79726.1 | Desal_0043 | Desal_1664 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | KEGG: geo:Geob_2863 hypothetical protein. | 0.625 |