node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS80093.1 | ACS81674.1 | Desal_2033 | Desal_3628 | TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: pca:Pcar_1807 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: scl:sce1037 NDP-sugar oxidoreductase. | 0.919 |
ACS80093.1 | metK | Desal_2033 | Desal_1278 | TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: pca:Pcar_1807 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.798 |
ACS80418.1 | metK | Desal_2362 | Desal_1278 | TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; NmrA family protein; KEGG: noc:Noc_0999 NAD-dependent epimerase/dehydratase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.798 |
ACS81674.1 | ACS80093.1 | Desal_3628 | Desal_2033 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: scl:sce1037 NDP-sugar oxidoreductase. | TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: pca:Pcar_1807 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.919 |
ACS81674.1 | metK | Desal_3628 | Desal_1278 | PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: scl:sce1037 NDP-sugar oxidoreductase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.798 |
ACS81707.1 | ahcY | Desal_3661 | Desal_3077 | PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.957 |
ACS81707.1 | guaA | Desal_3661 | Desal_1552 | PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.663 |
ACS81707.1 | metE | Desal_3661 | Desal_0813 | PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.986 |
ACS81707.1 | metK | Desal_3661 | Desal_1278 | PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.957 |
ACS81822.1 | metK | Desal_3777 | Desal_1278 | PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: mca:MCA1165 NAD-dependent epimerase/dehydratase family protein. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.798 |
ahcY | ACS81707.1 | Desal_3077 | Desal_3661 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | 0.957 |
ahcY | guaA | Desal_3077 | Desal_1552 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.440 |
ahcY | metE | Desal_3077 | Desal_0813 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.981 |
ahcY | metK | Desal_3077 | Desal_1278 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.867 |
guaA | ACS81707.1 | Desal_1552 | Desal_3661 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | 0.663 |
guaA | ahcY | Desal_1552 | Desal_3077 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.440 |
guaA | metK | Desal_1552 | Desal_1278 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.854 |
hldD | metK | Desal_0613 | Desal_1278 | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.798 |
metE | ACS81707.1 | Desal_0813 | Desal_3661 | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | PFAM: homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG: dde:Dde_2115 methionine synthase (B12-dependent). | 0.986 |
metE | ahcY | Desal_0813 | Desal_3077 | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.981 |