STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (330 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
ACS78939.1
PFAM: Radical SAM domain protein; KEGG: tdn:Suden_0182 radical SAM family protein.
 
  
 0.921
ACS78902.1
MoeA domain protein domain I and II; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.907
ACS78903.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.907
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.905
ACS80676.1
TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: dvm:DvMF_1339 molybdenum cofactor synthesis domain protein.
 
  
 0.904
folE2
Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
  0.900
mobA
Molybdenum cofactor synthesis domain protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 
 0.847
ACS79050.1
Adenylate/guanylate cyclase with GAF and PAS/PAC sensors; KEGG: sfu:Sfum_0907 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; PAS fold domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein.
  
 0.836
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.831
Your Current Organism:
Desulfovibrio salexigens
NCBI taxonomy Id: 526222
Other names: D. salexigens DSM 2638, Desulfovibrio salexigens ATCC 14822, Desulfovibrio salexigens DSM 2638, Desulfovibrio salexigens str. DSM 2638, Desulfovibrio salexigens strain DSM 2638
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.